Regulatory T cells suppress autoreactive CD4+ T cell response to bladder epithelial antigen

doi:10.5411/wji.v6.i2.105

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World Journal of Immunology

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2219-2824

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Immunol. Jul 27, 2016; 6(2): 105-118
Published online Jul 27, 2016. doi: 10.5411/wji.v6.i2.105

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Figure 4 OT-II CD4⁺ T cells gain activation in the bladder draining lymph nodes of urothelium-ovalbumin/OT-II mice. BLN cells of URO-OVA/OT-II mice (8 wk) were analyzed for surface CD44, CD45RB, CD62L, and CD69 by flow cytometry. Age-matched B6/OT-II mice were included for comparison. Gate was set on CD4⁺ T cells. Results are representative of 3 separate experiments consisting of 5 mice per group. Filled histograms: B6/OT-II mice; Gray line histograms: URO-OVA/OT-II mice. URO/OT-II: Urothelium-ovalbumin/OT-II mice; BLN: Bladder draining lymph nodes.

Citation: Liu WJ, Luo Y. Regulatory T cells suppress autoreactive CD4⁺ T cell response to bladder epithelial antigen. World J Immunol 2016; 6(2): 105-118
URL: https://www.wjgnet.com/2219-2824/full/v6/i2/105.htm
DOI: https://dx.doi.org/10.5411/wji.v6.i2.105