Review
Copyright ©The Author(s) 2015.
World J Immunol. Nov 27, 2015; 5(3): 99-112
Published online Nov 27, 2015. doi: 10.5411/wji.v5.i3.99
Figure 2
Figure 2 Components of the super elongation complex. ELL2 is part of the super elongation complex important for releasing RNA polymerase II from pausing. Cdk9 phosphorylates the ser-2 of the heptad repeats in the carboxyl-terminal domain of RNAP-II, negative elongation factor negative elongation factor, and DRB sensitive factor the DRB-sensitive factor, which becomes activated. ELL2: Eleven lysine rich leukemia protein 2; Cdk9: Cyclin dependent kinase 9.