Antimicrobial lipids: Emerging effector molecules of innate host defense

Figure 2 Working model of epithelial cell mediated innate defense. In response to microbial products and cytokines epithelial cells increase the production and secretion of antimicrobial lipids and antimicrobial proteins as well as cytokines and chemokine to eradicate infection in concert with other defense components of the body. PRR: Pattern recognition receptor for microbial products; AML: Antimicrobial lipids; AMP: Antimicrobial proteins. Other sources: Other defense cells recruited to the site of infections such as macrophages and neutrophils.