Chronic kidney disease after radical nephrectomy for suspected renal cancers

Table 2 Risk factors associated with new-onset chronic kidney disease or acceleration of pre-existing chronic kidney disease after radical nephrectomy

Risk factor	Odds ratio (95%CI); P-value	Ref.
Diabetes mellitus	11.60 (1.39-97.04); P = 0.024	Brandina et al[24]
	2.74 (1.07-6.98); P = 0.035	Cho et al[30]
Hypertension	3.67 (1.28-10.48); P = 0.015	Brandina et al[24]
Low preoperative GFR (< 90 mL/min per 1.73 m2)	3.30 (1.16-9.37); P = 0.025	Brandina et al[24]
Preoperative GFR (per 10 mL/min per 1.73 m2 rise)	0.47 (0.36-0.60); P = 0.0001	Cho et al[30]
Postoperative AKI	4.24 (2.28-7.89); P = 0.0001	Cho et al[30]
Adjacent non-neoplastic kidney parenchyma abnormalities
Arteriosclerosis > 50%	3.33 (1.03-10.79); P = 0.045	Brandina et al[24]
Interstitial fibrosis (present)	3.78 (1.32-10.76); P = 0.013
Glomerulosclerosis ≥ 5%	3.78 (1/24-11.50); P = 0.0061

AKI: Acute kidney injury; GFR: Glomerular filtration rate.