Perioperative outcomes and survival of radical cystectomy as a function of body mass index

Table 1 Preoperative patient characteristics

		Normal Weight(BMI 18.5-24.9)	Underweight(BMI < 18.5)	Overweight(BMI 25.0-29.9)	Obese(BMI > 30)	P value
Age at surgery (median, IQR), yr		70 (63-76)	78 (68-79)	70 (61-76)	67 (58-72)	0.126
Gender	Male	74 (66%)	4 (44%)	130 (81%)	106 (75%)	0.005
	Female	39 (35%)	5 (56%)	30 (19%)	36 (25%)
Clinical tumor stage	cT0	1 (1%)	0 (0%)	1 (1%)	1 (1%)	0.05
	cTis	0 (0%)	0 (0%)	8 (5%)	11 (8%)
	cTa	7 (7%)	1 (11%)	9 (6%)	10 (8%)
	cT1	30 (28%)	2 (22%)	26 (17%)	35 (26%)
	cT2	65 (61%)	4 (44%)	103 (67%)	67 (50%)
	cT3	3 (3%)	2 (22%)	4 (3%)	5 (4%)
	cT4	1 (1%)	0 (0%)	3 (2%)	4 (3%)
Prior intravesical therapy	No	86 (78%)	6 (67%)	113 (71%)	83 (59%)	0.018
	Yes	25 (22%)	3 (33%)	47 (29%)	57 (41%)
Prior neoadjuvant chemotherapy	No	100 (90%)	9 (100%)	150 (94%)	129 (92%)	0.478
	Yes	11 (10%)	0 (0%)	9 (6%)	11 (8%)
Race	Caucasian	105 (92%)	9 (100%)	151 (94%)	134 (94%)	0.492
	Hispanic	3 (3%)	0 (0%)	0 (0%)	0 (0%)
	Black	3 (3%)	0 (0%)	6 (4%)	7 (5%)
	Asian	1 (1%)	0 (0%)	2 (1%)	0 (0%)
	Unknown	1 (1%)	0 (0%)	1 (1%)	1 (1%)
Hypertension	No	52 (46%)	2 (22%)	73 (46%)	33 (23%)	< 0.001
	Yes	60 (54%)	7 (78%)	87 (54%)	108 (77%)
Diabetes mellitus, type II	No	99 (88%)	8 (89%)	132 (82%)	100 (71%)	0.006
	Yes	13 (12%)	1 (11%)	28 (18%)	40 (29%)
Coronary artery disease	No	89 (80%)	9 (100%)	125 (78%)	103 (74%)	0.248
	Yes	23 (20%)	0 (0%)	35 (22%)	37 (26%)
Cardiac arrhythmia	No	102 (91%)	7 (78%)	143 (89%)	129 (92%)	0.491
	Yes	10 (9%)	2 (22%)	17 (11%)	11 (8%)
History of coronary vascular accident	No	106 (95%)	8 (89%)	156 (97%)	139 (99%)	0.068
	Yes	6 (5%)	1 (11%)	4 (3%)	1 (1%)
Pulmonary disease	No	94 (84%)	7 (78%)	147 (92%)	115 (82%)	0.063
	Yes	18 (16%)	2 (22%)	13 (8%)	25 (18%)
Liver disease	No	110 (98%)	8 (89%)	159 (99%)	138 (99%)	0.077
	Yes	2 (2%)	1 (11%)	1 (1%)	1 (1%)
Nephrolithiasis	No	101 (91%)	9 (100%)	149 (93%)	126 (90%)	0.606
	Yes	10 (9%)	0 (0%)	11 (7%)	14 (10%)
Preoperative renal function	Normal	58 (72%)	7 (88%)	79 (70%)	70 (71%)	0.652
	CKD stage 3	19 (24%)	1 (12%)	31 (28%)	26 (27%)
	CKD stage 4	2 (2%)	0 (0%)	2 (2%)	2 (2%)
	CKD stage 5	2 (2%)	0 (0%)	0 (0%)	0 (0%)
Smoking history	No	27 (24%)	1 (11%)	42 (27%)	36 (26%)	0.76
	Yes	84 (76%)	8 (89%)	116 (73%)	103 (74%)

BMI: Body mass index; CKD: Chronic kidney disease; IQR: Inter-quartile range.