Diagnostic and therapeutic considerations for primary penal synovial sarcoma with specific MDM2 gene amplification: A case report

Figure 4 The immunohistochemistry images of the patient after surgery. A: Immunohistochemistry showed that the MDM2 protein was mainly located in the cell nucleus; B: Distinct staining signals could be observed in the cell nuclei, forming a sharp contrast with the nuclei of surrounding non-amplified cells. In the tumor tissue sections, strong positive staining for MDM2 could be detected in almost the entire tumor area; C: Schematic diagram of MDM2 gene amplification.