Oral medications regarding their safety and efficacy in the management of patent ductus arteriosus

doi:10.5409/wjcp.v5.i1.75

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Feb 8, 2016 (publication date) through Oct 2, 2024

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Pediatr. Feb 8, 2016; 5(1): 75-81
Published online Feb 8, 2016. doi: 10.5409/wjcp.v5.i1.75

Table 2 Comparison of adverse effects of oral ibuprofen and paracetamol[3]

	Oral ibuprofen	Oral paracetamol
Renal side effects	+/-	-
NEC	+	-
Spontaneous intestinal perforation	+	-
Gastrointestinal system bleeding	++	-
IVH	+	-
BPD	+/-	-
Alteration of platelet function	+	-
Decrease in cerebral blood flow	-	-
Hyperbilirubinemia	+/-	-
Hypertransaminasemia	-	+

NEC: Necrotizing enterocolitis; IVH: Intraventricular hemorrhage; BPD: Bronchopulmonary dysplasia.

Citation: Oncel MY, Erdeve O. Oral medications regarding their safety and efficacy in the management of patent ductus arteriosus. World J Clin Pediatr 2016; 5(1): 75-81
URL: https://www.wjgnet.com/2219-2808/full/v5/i1/75.htm
DOI: https://dx.doi.org/10.5409/wjcp.v5.i1.75