Tramadol use in pediatric sickle cell disease patients with vaso-occlusive crisis

Table 3 Paired admissions statistical analysis (n = 7)

	Morphine	Morphine + tramadol	P-value1
Morphine requirement (mg/kg per day), mean ± SD	0.77 ± 0.44	0.71 ± 0.57	0.50
Pain score, median (range)	5.5 (2-8)	6.5 (3-8)	0.27
PCA duration (d), median (range)	6 (4-13)	7 (3-10)	0.35
LOS (d), median (range)	7 (5-14)	9 (3-12)	0.61
Respiratory rate, mean (range)	19 (14-20)	19 (17-23)	0.87
Polyethylene glycol dose (gm/kg per day), mean (range)	0.55 (0.28-1.1)	0.41 (0.28-0.98)	0.67

¹P-value calculated using Wilcoxon Rank Sum test. PCA: Patient-controlled analgesia; LOS: Length of stay.