Systematic Reviews
Copyright ©The Author(s) 2025.
World J Clin Pediatr. Jun 9, 2025; 14(2): 103323
Published online Jun 9, 2025. doi: 10.5409/wjcp.v14.i2.103323
Table 2 The psychological mechanisms underlying various functional gastrointestinal disorders
FGID
Psychological mechanisms
Infant colicPsychosocial stress: High parental stress and anxiety may contribute to infant colic through alterations in caregiving responses and infant stress reactivity
Parent-infant interaction: Stressful caregiving environments and ineffective soothing strategies may exacerbate colic symptoms
Family dynamics: Parental conflict or lack of support can increase stress levels, impacting infant behavior and gastrointestinal symptoms
Functional constipationPsychosocial stress: Stress from social or academic pressures can affect bowel habits and lead to constipation
Emotional regulation: Difficulty managing emotions may result in withholding behavior, contributing to constipation
Family dynamics: Overcontrolling or punitive parenting styles regarding toilet training may increase constipation risk
Coping mechanisms: Ineffective coping strategies or anxiety about bowel movements can exacerbate symptoms
GERPsychosocial stress: Stress can affect gastrointestinal motility and increase acid reflux symptoms
Emotional regulation: Stress or anxiety may exacerbate ger symptoms by increasing gastric acid production or sensitivity
Family dynamics: High-stress family environments may influence feeding practices and exacerbate reflux symptoms
DiarrheaPsychosocial stress: Stress and anxiety can affect gut motility and contribute to episodes of diarrhea
Emotional regulation: Difficulty managing stress can lead to gastrointestinal disturbances, including diarrhea
Family dynamics: Family stressors or dysfunctional family environments may impact bowel habits and exacerbate diarrhea
IBSPsychosocial stress: Stress and anxiety play a significant role in IBS, influencing symptoms through the brain-gut axis
Emotional regulation: Difficulty managing emotions can lead to altered gut motility and heightened sensitivity
Family dynamics: Dysfunctional family environments or high levels of family stress may exacerbate IBS symptoms.
Coping mechanisms: Ineffective coping strategies may lead to somatization of stress
Cyclic vomiting syndromePsychosocial stress: Stressful events or emotional distress can trigger episodes of cyclic vomiting
Emotional regulation: Poor emotional regulation may contribute to the severity and frequency of vomiting episodes
Family dynamics: Stressful family environments or parental anxiety can impact the frequency and intensity of episodes
Dysfunctional abdominal painPsychosocial stress: Emotional stress and psychosocial factors can contribute to chronic abdominal pain through the brain-gut axis
Emotional regulation: Ineffective emotional regulation can lead to persistent pain perception
Family dynamics: Family stress and conflicts may exacerbate symptoms by affecting the child’s emotional state
Coping mechanisms: Poor coping strategies and somatization of stress may perpetuate pain symptoms
Abdominal migrainePsychosocial stress: Stress can trigger episodes of abdominal migraine by affecting the brain-gut axis and stress-response systems
Emotional regulation: Poor emotional regulation can lead to somatization of stress and exacerbate symptoms
Family dynamics: Parental stress or emotional instability can impact the child’s susceptibility to abdominal migraines
Early life stressors: Trauma or adverse experiences can alter stress-response systems, contributing to abdominal migraine
Coping mechanisms: Ineffective coping strategies may exacerbate the frequency and severity of episodes