Systematic Reviews
Copyright ©The Author(s) 2025.
World J Clin Pediatr. Jun 9, 2025; 14(2): 103323
Published online Jun 9, 2025. doi: 10.5409/wjcp.v14.i2.103323
Table 1 Key findings from the review
Factor
Prevalence (%)
Impact
Anxiety62Exacerbates FGID symptoms via stress reactivity and visceral hypersensitivity
Depression38Linked to altered pain perception, appetite changes, and fatigue
ADHD24Impulsivity and poor regulation worsen eating patterns and symptom severity
Emotional dysregulation58Leads to somatization and heightened symptom perception
High-stress family dynamics≥ 50Contributes to increased symptom severity and emotional insecurity
School stress41Triggers FGID symptoms during academic or social pressures
Early-life trauma46Disrupts HPA axis and gut-brain communication, worsening long-term outcomes
Visceral hypersensitivity54Amplifies pain perception to normal gut stimuli