Uveitis associated with juvenile idiopathic arthritis and chronic idiopathic uveitis in children: A retrospective cohort study

Table 4 Comparative analysis of patients with uveitis with unilateral and bilateral involvement

Parameter	Unilateral (n = 67)	Bilateral (n = 82)	P value
Females	34 (50.7)	49 (59.8)	0.321
Age at diagnosis of uveitis (years)			0.880
Mean	7.1	7.2
Median (25%, 75%)	6.1 (4.4, 8.4)	6.5 (4.2, 9.8)
Min–max	2.3-17.7	1.5–16.8
Age at diagnosis of arthritis (years)			0.710
Mean	6.4	6.5
Median (25%, 75%)	5.7 (3.8, 8.3)	5.4 (2.4, 10.4)
Min–max	1.2–14.2	1.0–16.2
Anatomical type of uveitis			0.082
Anterior	52 (77.6)	48 (58.5)
Pars planitis	1 (1.5)	5 (6.1)
Posterior	3 (4.5)	5 (6.1)
Panuveitis	11 (16.4)	24 (29.3)
Manifested (“red-eye”) uveitis	32 (47.8)	25/62 (40.3)	0.042
Human leukocyte antigen-B27 (+)	17/34 (50.0)	6/38 (15.8)	0.002
Eye complications at first examination	17 (25.4)	29 (35.4)	0.215
Antinuclear antibodies positivity	33/64 (51.6)	47/75 (62.7)	0.229
Uveitis appearance			0.115
Before arthritis	18 (26.9)	13 (15.9)
Simultaneously with arthritis	9 (13.4)	10 (12.2)
After arthritis	21 (31.3)	38 (46.3)
Unknown	1 (1.5)	0 (0.0)
Chronic idiopathic uveitis	18 (26.9)	21 (25.6)
C-reactive protein (mg/L)			0.194
Mean	23.8	19.3
Median (25%, 75%)	3.7 (1.0, 23.0)	1.0 (1.0, 15.2)
Min–max	0.1–192.0	0.0–133.0
ESR (mm/hour)			0.086
Mean	30.5	22.7
Median (25%, 75%)	24.0 (11.0, 49.0)	17.0 (7.0, 26.0)
Min–max	4.0–78.0	2.0–77.0
Active joint at onset			0.698
Mean	1.9	1.8
Median (25%, 75%)	1.0 (1.0, 2.0)	1.0 (1.0, 2.0)
Min–max	1.0–6.0	1.0–7.0

Data are presented as n (%). Max: Maximum; Min: Minimum.