Clinical, laboratory, and therapeutic differences between immunoglobulin E-mediated and non-immunoglobulin E-mediated cow’s milk protein allergy in children

Table 4 Types of feeding in children with cow’s milk protein allergy, n (%)

Feeding type1	Total, n = 586 (98.5)	IgE-mediated, n = 135 (23.0)	Non-IgE-mediated, n = 451 (77.0)	P valuea
Exclusive formula feeding	295 (50.3)	70 (51.9)	225 (49.9)	0.696
Both breast and formula-feeding	243 (41.5)	54 (40.0)	189 (41.9)	0.765
Exclusive breastfeeding	48 (8.2)	11 (8.1)	37 (8.2)	1.000
Type of formula used (n = 532)
Amino acid-based formula	322 (60.5)	82 (66.1)	240 (58.8)	0.173
Extensively hydrolyzed formula	300 (56.4)	65 (52.4)	237 (58.1)	0.301
Standard formula	42 (7.9)	8 (6.5)	34 (8.3)	0.573
Partially hydrolyzed formula	31 (5.8)	4 (3.2)	27 (6.6)	0.192
Anti-regurgitation formula	17 (3.2)	6 (4.8)	11 (2.7)	0.247
Plant-based milk formula	15 (2.8)	4 (3.2)	11 (2.7)	0.759
Lactose-free formula	7 (1.3)	3 (2.4)	4 (1.0)	0.208
High energy intake (n = 580)	64 (11.0)	21 (15.6)	43 (7.9)	0.061
Carbohydrate supplement	37 (6.4)	12 (8.9)	25 (5.6)	0.226
High-energy milk formula	35 (6.0)	12 (8.9)	23 (5.2)	0.146

Data are presented as numbers and percentages.

^aFisher’s exact test.

¹Some patients used more than one type of formula.

IgE: Immunoglobulin E.