Molecular profiles and long-term outcomes of Thai children with hepatic glycogen storage disease in Thailand

Table 4 Biochemical profiles at the diagnosis and the last follow-up, median (25^th-75^th percentiles)

Blood test	At the diagnosis	At the last follow-up	P value
Hb (mg/dL)	11.9 (10.1-12.2)	12.9 (11.8-13.1)	0.072
WBC	11140 (9975-14020)	9415 (8600-10690)	0.046
Platelet	386000 (325500-457500)	377500 (327000-448000)	1
Blood sugar (mg/dL)	55 (30-87)	72 (58-83.5)	0.248
Total cholesterol	241 (138-256)	174.5 (137-194.5)	0.132
Triglyceride (mg/dL)	231 (159-335)	105.5 (94.5-163.5)	0.037
LDL (mg/dL)	141 (88-211)	94 (83.5-122)	0.165
HDL (mg/dL)	24 (10-32)	39.5 (35-41)	0.004
Uric acid (mg/dL)	5.1 (3.9-6.5)	6 (5.6-7.55)	0.148
ALT (U/L)	665 (67-854)	59 (28-232.5)	0.021
AST (U/L)	833 (374-1704)	63.5 (33-335.5)	0.007
Total bilirubin (mg/dL)	0.39 (0.24-0.99)	0.53 (0.43-0.70)	0.462
Direct bilirubin (mg/dL)	0.22 (0.10-0.41)	0.22 (0.16-0.28)	1
Globulin (mg/dL)	3.1 (2.8-3.4)	3.4 (2.85-4.05)	0.354
Albumin (mg/dL)	4.3 (4.0-4.5)	4.4 (4.25-4.4)	0.335
GGT	169 (66.2-251)	59 (31.5-136)	0.156
Blood urea nitrogen	12 (8-14)	10.5 (9.5-13.5)	0.771
Creatinine	0.25 (0.21-0.4)	0.41 (0.26-0.55)	0.072

Hb: Hemoglobin; WBC: White blood cell count; LDL: Low density lipoprotein; HDL: High density lipoprotein; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transferase.