Molecular profiles and long-term outcomes of Thai children with hepatic glycogen storage disease in Thailand

Table 3 Patient characteristics, biological profiles at the time of clinical diagnosis and at the last of follow-up

Patient number	Sex	Age at clinical Dx (year)	Time from clinical Dx to molecular Dx (year)	First presentation	Growth and nutritional status	Biochemical result						Follow-up time (year)	Clinical and biological profiles at the last follow-up
						AST (U/L)	ALT (U/L)	BS (mg/dL)	TC (mg/dL)	TG (mg/dL)	Uric Acid (mg/dL)		Growth and nutritional status	AST (U/L)	ALT(U/L)	BS (mg/dL)	TC (mg/dL)	TG (mg/dL)	Uric Acid (mg/dL)
GSD I
5	F	14.7	12.52	Hepatomegaly, recurrent epistaxis	Wasting/ stunting	118	67	53	210	376	8.6	13.8	Stunting	33	28	58	179	396	9.7
GSD III
3	F	3.02	8.49	Hepatomegaly	Normal	4302	1341	48	241	622	5.1	11.5	Overweight	510	375	72	205	124	8
4	F	1.43	12.22	Hepatomegaly	Normal	629	547	20	138	119	3.3	12.3	Normal	33	28	78	137	63	5.8
6	M	2.62	3.06	Hepatomegaly, doll-like facies	Stunting	1878	854	30	180	231	6.1	3.1	Normal	626	408	35	184	203	6.8
GSD VI
2	F	1.75	9.24	Hepatomegaly	Wasting	746	736	56	305	335	6.9	12.5	Normal	15	14	83	137	89	6.1
7	F	3.08	2.08	Hepatomegaly	Stunting	72	64	92	256	189	4.3	2.1	Normal	55	40	72	226	104	5.9
8	M	1.35	1.10	Hepatomegaly, doll-like facies	Overweight/ stunting	920	665	55	246	303	3.9	1.8	Overweight	72	90	86	170	100	5.4
GSD IX
1	M	1.7	2.75	Hepatomegaly, doll-like facies	Stunting	1531	439	34	145	159	5.3	6.48	Overweight/stunting	161	78	84	145	97	5.2

GSD: Glycogen storage disease; F: Female; M: Male, Dx: Diagnosis; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; BS: Blood sugar; TC: Total cholesterol; TG: Triglyceride.