Evaluation of thyroid profile among children aged 1-15 years with nephrotic syndrome: An observation study

Table 2 Biochemical parameters in study subjects, n = 70

Parameter	Newly diagnosed	1st relapse	2nd relapse	Frequent relapse	P value1
Free T3	2.77 ± 0.37	2.93 ± 0.16	2.57 ± 0.47	2.50 ± 0.39	0.01
Free T4	0.91 ± 0.19	0.95 ± 0.11	0.84 ± 0.27	0.78 ± 0.12	0.03
TSH	4.83 ± 0.76	4.74 ± 1.17	5.81 ± 1.78	5.86 ± 1.56	< 0.01
GFR	69.61 ± 17.79	69.46 ± 15.20	64.52 ± 13.85	59.90 ± 12.10	< 0.01
T. Cholesterol	398.90 ± 67.25	432.0 ± 48.63	482.13 ± 48.63	476.91 ± 70.74	0.10
TG	411.0 ± 92.72	424.62 ± 82.79	433.07 ± 138.90	500.45 ± 151.38	0.27
LDL	396.64 ± 50.76	415.15 ± 53.30	416.40 ± 67.30	435.82 ± 67.54	0.16

¹ANOVA test or Kruskal–Wallis H test was used.

GFR: Thyroid-stimulating hormone; LDL: Low-density lipoprotein; TG: Thyroglobulin; TSH: Glomerular filtration rate.