Transcranial direct current stimulation as early augmentation in adolescent obsessive compulsive disorder: A pilot proof-of-concept randomized control trial

Table 3 Comparison of mean reduction in Children’s Yale-Brown obsessive-compulsive scale total score between 2 groups across different follow-up periods, mean ± SD

Change in C-YBOCS scores	Active tDCS (n = 10)	Sham tDCS (n = 8)	U value	P value
Baseline vs 2 wk
Obsessions	6.2 ± 4.26	2.37 ± 0.99	18	0.056
Compulsions	5.6 ± 3.75	2.87 ± 1.76	22	0.121
Total	11.8 ± 7.77	5.25 ± 2.22	18	0.056
Baseline vs 6 wk
Obsessions	7.0 ± 3.90	4.87 ± 1.53	22.5	0.131
Compulsions	6.5 ± 3.75	4.5 ± 2.64	25	0.312
Total	11.6 ± 6.93	9.37 ± 2.87	28	0.307
Baseline vs 12 wk
Obsessions	11.2 ± 1.66	9.0 ± 4.0	27.5	0.285
Compulsions	10.0 ± 2.0	7.5 ± 3.2	19	0.069
Total	13.8 ± 8.68	11.25 ± 3.34	29.5	0.373

tDCS: Transcranial direct current stimulation; CY-BOCS: Children’s Yale-Brown obsessive-compulsive scale.