Systemic juvenile idiopathic arthritis–associated lung disease: A retrospective cohort study

Figure 3 Brief summary of the pathogenesis of lung involvement in systemic juvenile arthritis. BMPR2: Bone morphogenetic protein receptor type II; GM-CSF: Granulocyte-macrophage colony-stimulating factor; IFN: Interferon; IL: Interleukin; ILD: Interstitial lung disease; MAS: Macrophage activation syndrome; PAH: Pulmonary arterial hypertension; PAP: Pulmonary alveolar proteinosis; sJIA: Systemic juvenile idiopathic arthritis; TNF: Tumor necrosis factor.