Salivary C-reactive protein and mean platelet volume as possible diagnostic markers for late-onset neonatal pneumonia

Table 3 Validity (area under the curve, sensitivity, specificity) of mean platelet volume, salivary C-reactive protein, serum C-reactive protein, and serum C-reactive protein/mean platelet volume to discriminate patients from controls

Parameter	AUC	95%CI	P value	Cut-off value	Sensitivity	Specificity	PPV	NPV
MPV	0.87	0.77–0.97	< 0.001a	> 8.8	86.67	80.0	81.2	85.7
Serum CRP	0.81	0.70–0.92	< 0.001a	> 6 mg/dL	76.67	60.0	65.7	72.0
sCRP	0.80	0.68–0.92	< 0.001a	> 3.5 mg/dL	76.67	83.33	82.1	78.1

^aP < 0.05.

AUC: Area under the curve; CI: Confidence interval; CRP: C-reactive protein; MPV: Mean platelet volume; NPV: Negative predictive value; PPV: Positive predictive value; sCRP: Salivary C-reactive protein.