Salivary C-reactive protein and mean platelet volume as possible diagnostic markers for late-onset neonatal pneumonia

Table 1 Demographic and laboratory findings of neonates with late-onset pneumonia and the control group

Parameter		Neonates with LOP, n = 40	Control group, n = 40	P value
Sex	M	21	22	> 0.05
	F	19	18	> 0.05
	M:F	1.1:1	1.2:1	> 0.05
Age in d		15 ± 4.6	14 ± 5	> 0.05
Anthropometric measurements at admission	Weight in g	3454 ± 360	3728 ± 316	< 0.0001a
	Length in cm	51.42 ± 1.0	51.87 ± 0.57	< 0.05a
	Head circumference	36.21 ± 0.8	36.7 ± 0.60	< 0.05a
Type of delivery	Normal	14 (35%)	16 (40%)	> 0.05
	CS	26 (65%)	24 (60%)	> 0.05
APGAR score	At 1 min	7.1 ± 2.5	7.4 ± 2.3	> 0.05
	At 5 min	8.5 ± 3.2	9 ± 2.9	> 0.05
Maternal illness	Non	31 (77.5%)	32 (80%)	> 0.05
	DM	3 (7.5%)	2 (5%)	> 0.05
	hypertension	2 (5%)	5 (12.5%)	> 0.05
	UTI	4 (10%)	3 (7.5%)	> 0.05
Serum CRP in mg/L		38.58 ± 24.9	3.60 ± 2.25	< 0.0001a
sCRP in mg/L		6.17 ± 3.38	3.07 ± 1.24	< 0.0001a
MPV		9.99 ± 0.94	8.42 ± 0.83	< 0.0001a
Serum CRP/MPV		3.86 ± 2.29	0.42 ± 0.39	< 0.0001a

^aP < 0.05.

Data are n, n (%), or mean ± SD. SCRP: C-reactive protein; CS: Caesarean section; DM: Diabetes mellitus; F: Female; LOP: Late-onset pneumonia; M: Male; MPV: Mean platelet volume; sCRP: Salivary C-reactive protein; UTI: Urinary tract infection.