Brain metabolic profile assessed by magnetic resonance spectroscopy in ‎‎children with Down syndrome: Relation to intelligence quotient

Table 3 Correlation between intelligence quotient and the brain metabolite ratios in children with down syndrome

Correlations with IQ	r	P value
F NAA/Cr	0.533	< 0.0011
F Cho/Cr	-0.210	0.193
F MI/Cr	-0.259	0.107
T NAA/Cr	0.215	0.182
T Cho/Cr	0.330	0.037
T MI/Cr	-0.018	0.913
BG NAA/Cr	0.100	0.541
BG Cho/Cr	0.105	0.518
BG MI/Cr	0.008	0.961
O NAA/Cr	0.091	0.578
O Cho/Cr	-0.346	0.029
O MI/Cr	0.215	0.184

¹P < 0.01 is significant.

BG: Basal ganglia; Cho: Choline; Cr: Creatine; DS: Down syndrome; F: Frontal; IQ: Intelligence quotient; MI: Myoinositol; NAA: N-acetyl aspartate; O: Occipital; T: Temporal.