Seronegative autoimmune hepatitis in childhood

doi:10.5409/wjcp.v12.i3.77

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Jun 9, 2023 (publication date) through Dec 26, 2024

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Pediatr. Jun 9, 2023; 12(3): 77-85
Published online Jun 9, 2023. doi: 10.5409/wjcp.v12.i3.77

Table 1 The antibodies and target antigens in autoimmune hepatitis

Antibody	Target antigen
ANA	Single-stranded/double-stranded DNA, ribonucleoproteins
ASMA	Filamentous actin, vimentin, desmin
LKM	Cytochrome P450 2D6 (CYP2D6)
anti-SLA	UGA serine transfer RNA associated protein
LC-1	Formiminotransferase cyclo-deaminase
pANCA	Nuclear lamina proteins
ASGP-R	Asialoglycoprotein receptor

ANA: Anti-nuclear antibody; ASMA: Anti-smooth muscle antibody; LKM: liver-kidney microsomal antibody; LC-1: Liver cytosol type-1 antibody; SLA: Anti-soluble liver antigen/liver–pancreas antigen; ASGP-R: Asialoglycoprotein receptor; pANCA: Perinuclear anti-neutrophil cytoplasmic antibody.

Citation: Islek A, Tumgor G. Seronegative autoimmune hepatitis in childhood. World J Clin Pediatr 2023; 12(3): 77-85
URL: https://www.wjgnet.com/2219-2808/full/v12/i3/77.htm
DOI: https://dx.doi.org/10.5409/wjcp.v12.i3.77