Frequency of celiac disease and distribution of HLA-DQ2/DQ8 haplotypes among siblings of children with celiac disease

doi:10.5409/wjcp.v11.i4.351

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World Journal of Clinical Pediatrics

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2219-2808

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Pediatr. Jul 9, 2022; 11(4): 351-359
Published online Jul 9, 2022. doi: 10.5409/wjcp.v11.i4.351

Table 2 The distribution of human leucocyte antigen genotypes of celiac patients and their siblings

HLA genotypes	Celiac patients, n = 57 (100%)	Siblings, n = 112 (100%)
HLA-DQ2	33 (57.9)	68 (60.7)
HLA-DQ2/DQ8	17 (29.8)	18 (16.1)
HLA-DQ8	6 (10.5)	15 (13.4)
Both negative	1 (1.8)	11 (9.8)

HLA: Human leucocyte antigen.

Citation: Sahin Y, Mermer S. Frequency of celiac disease and distribution of HLA-DQ2/DQ8 haplotypes among siblings of children with celiac disease. World J Clin Pediatr 2022; 11(4): 351-359
URL: https://www.wjgnet.com/2219-2808/full/v11/i4/351.htm
DOI: https://dx.doi.org/10.5409/wjcp.v11.i4.351