Non-surgical periodontal therapy: An update on current evidence

Table 3 Recommended systemic antibiotic dosing regimens

Single agent regimen dosage/duration
Amoxicillin	500 mg, three times per day × 8 d
Azithromycin	500 mg, once daily × 4-7 d
Ciprofloxacin	500 mg, twice daily × 8 d
Clindamycin	300 mg, three times daily × 10 d
Doxycycline or minocycline	100-200 mg, once daily × 21 d
Metronidazole	500 mg, three times daily × 8 d
Combination therapy
Metronidazole + amoxicillin	250 mg, of each three times daily × 8 d
Metronidazole + ciprofloxacin	500 mg of each twice daily × 8 d

Adapted from Krayer et al[41].