Copyright
©The Author(s) 2015.
World J Respirol. Mar 28, 2015; 5(1): 40-46
Published online Mar 28, 2015. doi: 10.5320/wjr.v5.i1.40
Published online Mar 28, 2015. doi: 10.5320/wjr.v5.i1.40
Figure 3 Possible mechanistic roles of p53 in pulmonary hypertension.
Hypoxia induces vascular proliferation via hypoxia-inducible factor-1α (HIF-1α) activation, which may be negatively regulated by p53 activation and also influence vascular remodeling induced by interleukin 6 (IL-6).
- Citation: Mizuno S, Bogaard HJ, Ishizaki T, Toga H. Role of p53 in lung tissue remodeling. World J Respirol 2015; 5(1): 40-46
- URL: https://www.wjgnet.com/2218-6255/full/v5/i1/40.htm
- DOI: https://dx.doi.org/10.5320/wjr.v5.i1.40