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Copyright ©The Author(s) 2015.
World J Respirol. Mar 28, 2015; 5(1): 40-46
Published online Mar 28, 2015. doi: 10.5320/wjr.v5.i1.40
Figure 2
Figure 2 The hypothetical role of p53 in chronic obstructive pulmonary disease. Oxidative stress from smoking activates the p53 pathway and thereby induces pulmonary emphysema through apoptosis of alveolar cells and vascular endothelial cells. The p53 pathway could be involved in bronchial remodeling.