Copyright
©The Author(s) 2015.
World J Respirol. Mar 28, 2015; 5(1): 40-46
Published online Mar 28, 2015. doi: 10.5320/wjr.v5.i1.40
Published online Mar 28, 2015. doi: 10.5320/wjr.v5.i1.40
Figure 1 Schematic illustration of regulation and pathway of p53.
Genotoxic stress or oxidative stress induce phosphorylation of mouse double minute 2 homolog (MDM2) and p53 protein and activate p53 pathway, which induce cell cycle arrest and/or apoptosis. Puma: P53 up-regulated modulator of apoptosis; Bax: Bcl-2-associated X protein.
- Citation: Mizuno S, Bogaard HJ, Ishizaki T, Toga H. Role of p53 in lung tissue remodeling. World J Respirol 2015; 5(1): 40-46
- URL: https://www.wjgnet.com/2218-6255/full/v5/i1/40.htm
- DOI: https://dx.doi.org/10.5320/wjr.v5.i1.40