Polymyxin B-immobilized fiber columns: A column to breathe new life into the treatment of interstitial lung disease?

Table 1 Representative reports of PMX-DHP for the treatment of intersititial lung diseases

Ref.	Publication year	Case		Comments
		n	Underlying disease
Seo et al[10]	2006	6	IPF, acute exacerbation	The first trial
Abe et al[11]	2012	160	IPF, acute exacerbation (73)	The largest cohort study
Teruya et al[12]	2013	1	Amyopathic dermatomyositis	Decrease in anti-CADM140/MDA5
				antibody titer observed
Sato et al[13]	2013	1	Amiodarone lung injury	Reduction of amiodarone and its derivative observed
Hara et al[14]	2011	33	Rapidly progressive ILD	Decrease in serum MCP-1 observed
			Resistant to steroid pulse therapy
Takada et al[15]	2014	26	IPF, acute exacerbation	The first case-control study
			Rapidly progressive ILD

IPF: Idiopathic pulmonary fibrosis; CADM: Clinically amyopathic dermatomyositis; MDA: Myeloma differentiation antigen; ILD: Interstitial lung disease; MCP-1: Monocyte chemotactic protein 1; PMX-DHP: Direct hemoperfusion with polymyxin B-immobilized fiber columns.