Effect of oxidative stress on development of silicosis

Table 3 Comparison of nitric oxide, superoxide dismutase, malondialdehyde, total antioxidant capacity, nitric oxide synthase and serum glutathione peroxidase between observation group and silicosis at different stages

Group	n	NO (μmol/L)	SOD (U/mL)	MDA (μmol/L)	T-AOC (U/mL)	NOS (μmol/L)	GSH-Px (U/mL)
Observation	32	74.130 ± 38.049	70.414 ± 20.036	4.489 ± 1.154	12.903 ± 3.790	35.379 ± 5.504	256.906 ± 21.418
Silicosis
Phase I	64	79.145 ± 36.149	69.215 ± 25.033	4.994 ± 1.237	12.905 ± 4.448	35.626 ± 7.234	259.594 ± 34.79
Phase II	46	80.173 ± 36.215	67.896 ± 26.018	5.038 ± 1.208	12.834 ± 3.481	36.078 ± 5.911	276.783 ± 40.969
Phase III	20	83.176 ± 34.131	67.201 ± 30.030	5.244 ± 1.127	13.993 ± 4.662	36.899 ± 4.162	290.750 ± 39.129ac

^aP < 0.05 vs observation group;

^cP < 0.05 vs phase I silicosis. NO: Nitric oxide; SOD: Superoxide dismutase; MDA: Malondialdehyde; T-AOC: Total antioxidant capacity; NOS: Nitric oxide synthase; GSH-Px: Serum glutathione peroxidase.