Effect of oxidative stress on development of silicosis

Table 2 Comparison of nitric oxide, superoxide dismutase, malondialdehyde, total antioxidant capacity, nitric oxide synthase and serum glutathione peroxidase between control, dust-exposed group and silicosis patient group

Group	n	NO (μmol/L)	SOD (U/mL)	MDA (μmol/L)	T-AOC (U/mL)	NOS (μmol/L)	GSH-Px (U/mL)
Control	100	45.622 ± 24.081	75.239 ± 24.020	4.027 ± 0.822	11.639 ± 3.707	33.812 ± 6.398	223.360 ± 46.838
Dust-exposed	200	77.148 ± 30.188b	70.515 ± 20.034b	4.240 ± 1.167	11.814 ± 4.758	35.598 ± 5.664	231.164 ± 36.484a
Silicosis	130	81.162 ± 35.176b	68.209 ± 21.528b	5.054 ± 1.204ad	13.048 ± 4.153ac	36.201 ± 7.782ac	270.469 ± 39.228bd

^aP < 0.05,

^bP < 0.01 vs control group;

^cP < 0.05,

^dP < 0.01 vs dust-exposed group. NO: Nitric oxide; SOD: Superoxide dismutase; MDA: Malondialdehyde; T-AOC: Total antioxidant capacity; NOS: Nitric oxide synthase; GSH-Px: Serum glutathione peroxidase.