Adenosine amine congener ameliorates cisplatin-induced hearing loss

Figure 4 Transferase mediated dUTP nick end labelling staining in the rat cochleae exposed to cisplatin. A: Apoptotic marginal cells (MC) of the stria vascularis (SV) in the control vehicle-treated cochlea; B: Reduced number of apoptotic marginal cells in the adenosine amine congener (ADAC)-treated cochlea; C: Terminal deoxynucleotidyl transferase mediated dUTP nick end labeling assay staining in the organ of Corti of the control vehicle-treated cochlea; D: Reduced apoptosis in the organ of Corti of the ADAC-treated cochlea. Images are single optical sections of the middle turn. IHC: Inner hair cells; OHC: Outer hair cells.