Effects of p27Kip1- and p53- shRNAs on kanamycin damaged mouse cochlea

doi:10.5319/wjo.v2.i1.1

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Feb 28, 2012 (publication date) through Dec 1, 2024

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World Journal of Otorhinolaryngology

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2218-6247

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Otorhinolaryngol. Feb 28, 2012; 2(1): 1-7
Published online Feb 28, 2012. doi: 10.5319/wjo.v2.i1.1

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Figure 4 Number of apoptotic cells in the mouse cochlea after kanamycin treatment and injections with adeno-associated virus-p53-short hairpin RNA and adeno-associated virus-p27 + p53-short hairpin RNA constructs. Differences in the level of apoptosis between adeno-associated virus (AAV)-short hairpin RNA (shRNA) and saline injected cochleae were statistically significant, ^bP < 0.001. AAV-p53-shRNA vs saline P = 0.00014; AAV-p27 + p53-shRNA vs saline P = 0.0011.

Citation: Pietola L, Jero J, Jalkanen R, Kinnari TJ, Jero O, Frilander M, Pajusola K, Salminen M, Aarnisalo AA. Effects of p27^Kip1- and p53- shRNAs on kanamycin damaged mouse cochlea. World J Otorhinolaryngol 2012; 2(1): 1-7
URL: https://www.wjgnet.com/2218-6247/full/v2/i1/1.htm
DOI: https://dx.doi.org/10.5319/wjo.v2.i1.1