Effects of p27Kip1- and p53- shRNAs on kanamycin damaged mouse cochlea

doi:10.5319/wjo.v2.i1.1

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Feb 28, 2012 (publication date) through Dec 1, 2024

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World Journal of Otorhinolaryngology

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2218-6247

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Otorhinolaryngol. Feb 28, 2012; 2(1): 1-7
Published online Feb 28, 2012. doi: 10.5319/wjo.v2.i1.1

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Figure 3 Adeno-associated virus-short hairpin RNAs in mouse cochlea. A: EGFP expression in mouse cochlea organ of Corti cotransduced with adeno-associated virus (AAV)-EGFP and AAV-short hairpin RNA (shRNA) (p27^Kip1+p53). Arrow shows EGFP-positive cell; FITC filter, Scale bar 200 μm; B: Uninjected control ear form the AAV-shRNA (p27^Kip1+p53) injected animal; Arrows point to apoptotic cells in organ of Corti, Scale bar 200 μm; C: NaCl injected animal’s ear; Arrows point to apoptotic cells in organ of Corti. Scale bar 200 μm.

Citation: Pietola L, Jero J, Jalkanen R, Kinnari TJ, Jero O, Frilander M, Pajusola K, Salminen M, Aarnisalo AA. Effects of p27^Kip1- and p53- shRNAs on kanamycin damaged mouse cochlea. World J Otorhinolaryngol 2012; 2(1): 1-7
URL: https://www.wjgnet.com/2218-6247/full/v2/i1/1.htm
DOI: https://dx.doi.org/10.5319/wjo.v2.i1.1