Effects of p27Kip1- and p53- shRNAs on kanamycin damaged mouse cochlea

doi:10.5319/wjo.v2.i1.1

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Feb 28, 2012 (publication date) through Feb 6, 2025

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World Journal of Otorhinolaryngology

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2218-6247

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Otorhinolaryngol. Feb 28, 2012; 2(1): 1-7
Published online Feb 28, 2012. doi: 10.5319/wjo.v2.i1.1

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Figure 2 Schematic representation of used adeno-associated virus constructs. The constructs are not drawn in scale. ITR: Adeno-associated virus inverted terminal repeats; CMV: Human cytomegalovirus promoter; U6: U6-promoter; EGFP: Enhanced green fluorescent protein coding sequence; shRNA: Small hairpin RNA; 1: shp27Kip1(2)/shp27Kip1(3); 2: shp53; 3: shp53/shp27Kip1(2)/shp27Kip1(3); WPRE: Woodchuck hepatitis virus post-transcriptional regulatory element; pA: SV40 polyadenylation signal.

Citation: Pietola L, Jero J, Jalkanen R, Kinnari TJ, Jero O, Frilander M, Pajusola K, Salminen M, Aarnisalo AA. Effects of p27^Kip1- and p53- shRNAs on kanamycin damaged mouse cochlea. World J Otorhinolaryngol 2012; 2(1): 1-7
URL: https://www.wjgnet.com/2218-6247/full/v2/i1/1.htm
DOI: https://dx.doi.org/10.5319/wjo.v2.i1.1