Glaucoma and Alzheimer's disease: Their clinical similarity and future therapeutic strategies for glaucoma

Figure 2 Changes in the cerebral blood flow of the temporal and parietal lobes (A), blood flow in the optic nerve head (C), and mean deviation (D) for each normal tension glaucoma patient after 6 mo of donepezil treatment, a representative change of SPECT images after 6 mo treatment (B). Arrows indicate obviously decreased CBF. ONH blood flow was evaluated by laser speckle flowgraphy, and the MD was obtained by the Humphrey visual field test (program 30-2). ^aP < 0.05, ^bP < 0.01 vs pretreatment, paired t-test. ONH: Optic nerve head; MD: Mean deviation; CBF: Cerebral blood flow.