Individualized misoprostol dosing for labor induction or augmentation: A review

Table 1 Comparison of titrated oral misoprostol in labor induction between studies

Ref.	Year	No. of women	Initial dosage (μg)	Dosing interval	Efficacy	Adverse effects	Cesarean rate (%)
Hofmeyr et al[18]	2001	25	20	q2h	72% VD within 32 h	8% UH	20.0
Hofmeyr et al[19]	2001	346	20	q2h	62% VD within 24 h	4% UH	16.0
Matonhodze et al[24]	2003	176	20	q2h	60.2% VD within 24 h	4% UH, 8% UT	14.0
Cheng et al[20]	2006	77	20	q1h	93.5% VD within 24 h	0% UH, 9.1% UT	3.9
Bricker et al[25]	2008	375	20	q2h	76% VD within 24 h	2% UH, 5% UT	14.0
Cheng et al[21]	2008	101	20	q1h	94.1% VD within 24 h	0% UH, 6.9% UT	4.0
Ho et al[22]	2010	112	20	q1h	94.6% VD within 24 h	0% UH, 7.1% UT	3.6
Souza et al[23]	2010	30	20	q1h	80% VD within 24 h	13.3% UT	20.0

VD: Vaginal delivery; UH: Uterine hyperstimulation; UT: Uterine tachysystole.