Comprehensive management of epithelial ovarian cancer with peritoneal metastases

Table 1 Intraoperative bidirectional chemotherapy orders

Add cisplatin (50 mg/m2) ________ mg to 2 L of 1.5% dextrose peritoneal dialysis solution

Add doxorubicin (15 mg/m2) ________ mg to same 2 L of 1.5% dextrose peritoneal dialysis solution

Add ifosfamide (1300 mg/m2) ________ mg to 1 L normal saline

Begin continuous iv infusion over 90 min simultaneous with ip chemotherapy

Add mesna disulfide (260 mg/m2) ________ mg in 100 mL 0.9% sodium chloride to be given iv as a bolus 15 min prior to ifosfamide infusion

Add mesna disulfide (260 mg/m2) ________ mg in 100 mL 0.9% sodium chloride to be given iv as a bolus 4 h after ifosfamide infusion

Add mesna disulfide (260 mg/m2) ________ mg in 100 mL 0.9% sodium chloride to be given iv as a bolus 8 h after ifosfamide infusion

Send all the above to operating room No. _______ at _______ o’clock on ___________ (date) for a 90-min treatment