Brief Article
Copyright ©2012 Baishideng.
World J Obstet Gynecol. Oct 10, 2012; 1(3): 35-39
Published online Oct 10, 2012. doi: 10.5317/wjog.v1.i3.35
Table 3 Serious adverse events observed in the two Austrian Arbeitsgemeinschaft für Gynäkologische Onkologie phase II studies using irinotecan + docetaxel or liposomal doxorubicin +/- gemcitabine + G-CSF in patients with platinum-resistant and platinum-refractory ovarian cancer n (%)
Type of SAEWeekly irinotecan + docetaxel (n = 15)Liposomal doxorubicin +/- gemcitabine (n = 12)
Subileus and fatigue03 (25)
Uncontrollable vomiting and fever02 (17)
Febrile neutropenia01 (8)
Pulmonary embolism/deep pelvic vein thrombosis2 (13)1 (8)
Pneumonia01 (8)
Significant pleural effusion01 (8)
Mucositis/diarrhea1 (7)1 (8)
Generalized edema01 (8)
Total number of SAE3 (20)11 (91)