Copyright
©2012 Baishideng.
World J Obstet Gynecol. Oct 10, 2012; 1(3): 20-28
Published online Oct 10, 2012. doi: 10.5317/wjog.v1.i3.20
Published online Oct 10, 2012. doi: 10.5317/wjog.v1.i3.20
Table 1 IGF-I receptor mutations
| Gene mutation | Birth weight (SD) | Birth height (SD) | Complications |
| Arg108Gln/Lys115Asn | -3.5 | -4.8 | Microcephaly, abnormal speech[29] |
| Arg59Ter | -3.5 | -3.0 | Microcephaly, Delay in speech[29] |
| Arg709Gln | -1.5 | -2.6 | Mental retardation[28] |
| Gly1050Lys | -2.1 | -4.0 | Insulin resistance[32] |
| Arg281Gln | -3.1 | -5.0 | Decreased cell proliferation[31] |
| Val599Glu | -2.3 | -2.1 | Developmental delay[33] |
| Gly1125Ala | -1.8 | -3.6 | Microcephaly, clinodactyly, delayed menarche, diabetes mellitus[30] |
- Citation: Zhang XQ. Intrauterine growth restriction and genetic determinants - existing findings, problems, and further direction. World J Obstet Gynecol 2012; 1(3): 20-28
- URL: https://www.wjgnet.com/2218-6220/full/v1/i3/20.htm
- DOI: https://dx.doi.org/10.5317/wjog.v1.i3.20