Copyright
©The Author(s) 2023.
World J Neurol. May 31, 2023; 9(3): 17-27
Published online May 31, 2023. doi: 10.5316/wjn.v9.i3.17
Published online May 31, 2023. doi: 10.5316/wjn.v9.i3.17
Table 3 Differences in composite DePaul symptom questionnaire-2 symptom scores
| Symptom | Alcohol intolerant | Not alcohol intolerant | P value |
| mean (SD) | mean (SD) | ||
| Post-exertional malaise | 79.53 (15.46) | 71.99 (17.07) | < 0.01 |
| Feeling drained | 74.70 (21.53) | 67.06 (23.31) | 0.01 |
| Minimum exercise | 78.99 (20.48) | 72.27 (20.62) | 0.01 |
| Worse after physical activity | 80.83 (21.42) | 74.22 (21.83) | 0.01 |
| Soreness | 77.84 (19.87) | 70.96 (20.40) | 0.01 |
| Fatigue | 81.86 (15.10) | 77.47 (15.88) | 0.02 |
| Heavy feeling | 83.87 (22.56) | 69.53 (30.82) | < 0.01 |
| Muscle fatigue | 76.80 (24.01) | 64.32 (26.03) | < 0.01 |
| Unrefreshing sleep | 81.52 (18.83) | 80.08 (20.80) | 0.57 |
| Cognitive impairment | 61.53 (18.28) | 54.92 (18.39) | < 0.01 |
| Difficulty remembering | 68.84 (22.51) | 64.58 (25.17) | 0.14 |
| Difficulty finding right word | 61.78 (23.69) | 54.56 (23.02) | 0.01 |
| Difficulty understanding | 51.02 (24.93) | 44.14 (24.33) | 0.02 |
| Absent-mindedness | 62.74 (24.94) | 57.50 (22.73) | 0.08 |
| Slowness of thought | 60.34 (24.78) | 52.99 (25.70) | 0.02 |
| Only focus on one thing | 68.96 (23.14) | 59.38 (24.60) | < 0.01 |
| Difficulty paying attention | 72.84 (23.31) | 66.97 (23.77) | 0.04 |
| Slowed speech | 35.75 (27.80) | 29.61 (24.33) | 0.07 |
| Mental tiredness | 71.32 (21.74) | 64.19 (23.55) | 0.01 |
| Fever and flu | 37.71 (19.81) | 33.74 (19.55) | 0.1 |
| Fever | 16.36 (21.41) | 14.71 (20.52) | 0.53 |
| High temperature | 33.82 (26.14) | 29.43 (26.09) | 0.18 |
| Flu-like symptoms | 52.84 (25.87) | 49.22 (27.97) | 0.27 |
| Prolonged viral illness recovery | 38.16 (32.95) | 35.68 (33.88) | 0.55 |
| Fluctuations in temperature | 47.18 (31.83) | 39.76 (31.38) | 0.06 |
| Pain | 54.84 (22.94) | 46.30 (21.86) | < 0.01 |
| Stomach pain | 45.11 (28.08) | 36.33 (25.14) | 0.01 |
| Irritable bowel | 51.98 (31.39) | 44.01 (31.88) | 0.04 |
| Bloating | 50.79 (28.83) | 41.45 (25.80) | 0.01 |
| Muscle pain | 71.45 (25.12) | 63.15 (29.43) | 0.02 |
| Sleep disruption | 57.63 (23.80) | 51.52 (25.12) | 0.04 |
| Problems staying asleep | 61.29 (28.62) | 54.04 (29.16) | 0.04 |
| Waking up early | 52.40 (28.64) | 44.53 (30.07) | 0.03 |
| Problems falling asleep | 61.29 (28.62) | 54.04 (29.16) | 0.39 |
| Orthostatic intolerance | 39.99 (23.21) | 27.86 (22.93) | < 0.01 |
| Graying or blacking out after standing | 28.14 (29.39) | 17.63 (24.90) | < 0.01 |
| Blurred or tunnel vision after standing | 35.52 (31.01) | 25.13 (28.51) | 0.01 |
| Heart beats quickly after standing | 50.12 (31.11) | 35.66 (33.37) | < 0.01 |
| Dizziness | 45.91 (26.21) | 33.85 (26.34) | < 0.01 |
| Genitourinary | 43.06 (26.18) | 36.81 (23.43) | 0.05 |
| Urinary urgency | 41.95 (30.88) | 38.03 (31.99) | 0.31 |
| Bladder problems | 36.96 (31.91) | 29.82 (27.29) | 0.05 |
| Nighttime urinary urgency | 50.18 (31.51) | 42.37 (30.20) | 0.04 |
| Temperature intolerance | 39.45 (22.76) | 28.60 (19.98) | < 0.01 |
| Chills or shivers | 37.38 (26.16) | 27.34 (24.01) | < 0.01 |
| Low temperature | 29.41 (28.02) | 17.45 (20.80) | < 0.01 |
| Cold limbs | 51.02 (28.65) | 41.02 (28.89) | 0.01 |
| Other | |||
| Needing to nap daily | 58.74 (28.63) | 53.39 (30.80) | 0.14 |
| Sleep inversion | 21.80 (30.09) | 16.28 (26.85) | 0.11 |
| Joint pain | 60.33 (31.88) | 56.64 (30.99) | 0.35 |
| Eye pain | 34.24 (29.25) | 25.52 (25.32) | 0.01 |
| Chest pain | 28.32 (23.57) | 19.79 (24.24) | < 0.01 |
| Headaches | 53.32 (26.10) | 45.18 (24.69) | 0.01 |
| Twitching | 38.28 (26.15) | 30.34 (24.25) | 0.01 |
| Muscle weakness | 68.15 (25.56) | 57.81 (25.92) | < 0.01 |
| Sensitivity to noise | 64.12 (25.50) | 57.55 (27.95) | 0.04 |
| Sensitivity to light | 58.53 (28.25) | 51.04 (29.00) | 0.03 |
| Unable to focus vision | 41.35 (26.21) | 33.06 (22.82) | 0.01 |
| Unable to focus attention | 56.63 (21.10) | 53.89 (20.75) | 0.31 |
| Loss of depth perception | 31.10 (31.76) | 17.63 (24.22) | < 0.01 |
| Nausea | 39.42 (24.74) | 26.04 (25.76) | < 0.01 |
| Feeling unsteady | 49.70 (28.00) | 36.85 (25.48) | < 0.01 |
| Shortness of breath | 38.88 (27.26) | 35.81 (26.07) | 0.36 |
| Irregular heartbeat | 32.91 (26.82) | 28.26 (26.79) | 0.16 |
| Losing weight | 19.04 (25.04) | 17.34 (19.65) | 0.6 |
| Gaining weight | 52.70 (33.53) | 47.58 (31.51) | 0.3 |
| Loss of appetite | 30.37 (24.52) | 31.12 (25.84) | 0.81 |
| Sweating hands | 15.99 (23.28) | 15.89 (24.97) | 0.97 |
| Night sweats | 37.44 (29.32) | 35.55 (30.20) | 0.61 |
| Feeling hot or cold | 53.93 (26.88) | 45.96 (26.93) | 0.02 |
| Sore throats | 37.50 (25.00) | 32.16 (24.11) | 0.08 |
| Lymph nodes | 39.54 (28.82) | 34.08 (27.50) | 0.12 |
| Sensitivity to smells | 53.43 (30.68) | 37.50 (30.99) | < 0.01 |
| Sensitivity to mold | 29.89 (37.74) | 21.45 (29.94) | 0.04 |
| Temperature intolerance | 72.52 (26.97) | 55.60 (31.93) | < 0.01 |
| Worse after mental activity | 66.41 (24.31) | 59.87 (28.53) | 0.06 |
| Feeling disoriented | 40.44 (25.23) | 33.68 (23.36) | 0.03 |
| Difficulty reading | 50.96 (32.42) | 39.34 (30.89) | < 0.01 |
| Eye aching | 40.44 (29.61) | 30.66 (28.47) | 0.01 |
| Sensitivity to pain | 53.50 (31.78) | 44.35 (36.19) | 0.04 |
| Pain from pressure | 27.00 (34.21) | 24.87 (33.73) | 0.62 |
| Daytime drowsiness | 64.24 (26.74) | 60.53 (27.85) | 0.27 |
| Sensitivity to vibrations | 36.34 (35.50) | 21.68 (31.39) | < 0.01 |
| Poor coordination | 51.68 (28.56) | 38.42 (25.08) | < 0.01 |
| Sinus infections | 25.00 (28.84) | 23.68 (25.36) | 0.69 |
| Upright position intolerance | 51.98 (32.87) | 44.08 (32.86) | 0.05 |
- Citation: Maciuch J, Jason LA. Alcohol intolerance and myalgic encephalomyelitis/chronic fatigue syndrome. World J Neurol 2023; 9(3): 17-27
- URL: https://www.wjgnet.com/2218-6212/full/v9/i3/17.htm
- DOI: https://dx.doi.org/10.5316/wjn.v9.i3.17