Atypical neurological symptoms associated with CGG expansions of the FMR1 gene

Figure 1 Pedigree structure of the patient 1 (arrow), they were 12 brothers and sisters, only those relevant are shown. Fragile X mental retardation (FMR1) CGG expanded alleles carriers are denoted as a grey filled symbol, they did not show any neurological disorder. Black filled symbols denote FMR1 CGG full mutation carriers affected by fragile X syndrome with mental retardation. Crossed symbol indicates deceased family members. Circle indicates females and square males.