P2X7 receptor in skin biology and diseases

doi:10.5314/wjd.v5.i2.72

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May 2, 2016 (publication date) through Nov 19, 2024

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World Journal of Dermatology

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2218-6190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Dermatol. May 2, 2016; 5(2): 72-83
Published online May 2, 2016. doi: 10.5314/wjd.v5.i2.72

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Figure 2 Activation of the P2X7 receptor and its regulation by CD39. Activation of P2X7 by extracellular ATP causes an influx of Ca²⁺ and Na⁺, and efflux of K⁺. Extracellular ATP can be degraded by cell surface CD39 to limit P2X7 activation on Langerhans cells, macrophages and mast cells. ATP: Adenosine triphosphate.

Citation: Geraghty NJ, Watson D, Adhikary SR, Sluyter R. P2X7 receptor in skin biology and diseases. World J Dermatol 2016; 5(2): 72-83
URL: https://www.wjgnet.com/2218-6190/full/v5/i2/72.htm
DOI: https://dx.doi.org/10.5314/wjd.v5.i2.72