Copyright
©The Author(s) 2016.
World J Dermatol. Feb 2, 2016; 5(1): 17-51
Published online Feb 2, 2016. doi: 10.5314/wjd.v5.i1.17
Published online Feb 2, 2016. doi: 10.5314/wjd.v5.i1.17
Table 4 Guidelines for monitoring psoriasis patients receiving methotrexate by utilizing PIIINP levels
| Indications for considering withdrawal of methotrexate | Elevation of PIIINP above 10.0 μg/L in at least 3 samples in one 12-mo period |
| Indications for considering liver biopsy | Elevation of pretreatment PIIINP above 8.0 μg/L |
| Elevation of PIIINP above 8.0 μg/L in 2 consecutive samples | |
| Elevation of PIIINP above the normal range (1.7-4.2 μg/L) in at least 3 samples over a 12 mo period | |
| Remarks: Serum for PIIINP measurement should be collected prior to starting methotrexate and should subsequently be measured every 2-3 mo during continued treatment | |
- Citation: Mahajan VK. Psoriasis treatment: Unconventional and non-standard modalities in the era of biologics. World J Dermatol 2016; 5(1): 17-51
- URL: https://www.wjgnet.com/2218-6190/full/v5/i1/17.htm
- DOI: https://dx.doi.org/10.5314/wjd.v5.i1.17