d-limonene prevents ultraviolet irradiation: Induced cyclobutane pyrimidine dimers in Skh1 mouse skin

Figure 5 d-Limonene induced the expression of filaggrin. A: Control; B: 100% d-limonene alone. Sebaceous glands of d-limonene–treated mice show a higher filaggrin signal compared to control mice. Also shown is the typical increased thickness of filaggrin-negative materials distal to the dark, thin filaggrin-positive layer, in comparison to control skin.