d-limonene prevents ultraviolet irradiation: Induced cyclobutane pyrimidine dimers in Skh1 mouse skin

doi:10.5314/wjd.v3.i3.64

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World Journal of Dermatology

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2218-6190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Dermatol. Aug 2, 2014; 3(3): 64-72
Published online Aug 2, 2014. doi: 10.5314/wjd.v3.i3.64

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Figure 1 d-Limonene prevented sunburn formation. Mice were exposed orally to 20 μL of pure or diluted d-limonene daily for 4 consecutive days followed by 1.5 kJ/ m² of ultraviolet B exposure generated by a commercial sunlamp 1 d later. The maximum sunburn response occurred as shown by skin erythema on 6th day of UVR exposure was completely eliminated by pure d-limonene. A: UVR alone; B: UVR + 1.0% d-limonene in liponate; C: UVR + 10% d-limonene in liponate; D: UVR + 100% d-limonene. Topical application of d-limonene followed by UVR yielded similar results (data not shown). UVR: Ultraviolet irradiation.

Citation: Uddin AN, Wu F, Labuda I, Tchou-Wong KM, Burns FJ. d-limonene prevents ultraviolet irradiation: Induced cyclobutane pyrimidine dimers in Skh1 mouse skin. World J Dermatol 2014; 3(3): 64-72
URL: https://www.wjgnet.com/2218-6190/full/v3/i3/64.htm
DOI: https://dx.doi.org/10.5314/wjd.v3.i3.64