RANK-ligand and osteoprotegerin as biomarkers in the differentiation between periprosthetic joint infection and aseptic prosthesis loosening

Figure 2 Serum parameters, loosened vs stable implants. Analysis of variance (Kruskal-Wallis-ANOVA) without assuming normal distribution with Dunn’s post-hoc test. RANKL and OPG serum levels showed no significant (ns) differences in the mean values between a stable and loose implant (A and B), nor did the other parameters as alkaline phosphatase (AP), boneAP, and serum phosphate (C-F). RANKL: RANK-ligand; OPG: Osteoprotegerin.