Bone regeneration with osteogenic matrix cell sheet and tricalcium phosphate: An experimental study in sheep

Figure 3 Hematoxylin and eosin-stained sections at 4 wk after implantation into the subcutaneous layer of athymic rats. A low-magnification image of a β-tricalcium phosphate (TCP) disc without the cell sheet shows poor bone formation (A and B). Conversely, a high level of bone formation is visible in and around TCP wrapped with an osteogenic matrix cell sheet cultured in minimum essential medium containing ascorbic acid and dexamethasone (C and D). Asterisks indicate bone tissue.