Total joint replacement in inhibitor-positive haemophilia: Long-term outcome analysis in fifteen patients

Table 1 Main surgical operations in patients (A and B) with the low historical inhibitor titre (< 5 BU/mL)

Patient and operations (model)	Haemophilia therapy	Primary haemostatic outcome	Surgical outcome
A
TKR (cruciate retaining)	Cryo (AHF-20) → pdFVIII	Good	Good
TKR (cruciate retaining)	pdFVIII	Good	Good
Ankle arthroplasty	pdfVIII	Good	Good
Ankle arthroplasty	pdFVIII	Good	Good
Knee revision arthroplasty (reconstructive)	rFVIII	Fair	Good
Knee revision arthroplasty (reconstructive)	rFVIII	Good	Good
B
Knee hemiarthroplasty (unicondylar)	pdFVIII	Good	Poor
Revision arthroplasty (cruciate retaining)	pdFVIII → rFVIIa	Fair	Good

In A, six operations and in B, two operations were performed. TKR: Total knee replacement; pdFVIII: Plasma-derived factor VIII; rFVIII: Recombinant FVIII.