Risk assessment instruments for screening bone mineral density in a Mediterranean population

Table 4 Receiver operating curve analysis using Greek population values for osteoporosis status

	Area	95%CI		Cut-off	Sensitivity	Specificity	PPV	NPV	P-value
SCORE1	0.678	0.640	0.717	20.75 >	72%	60%	36%	87%	< 0.0005
ORAI1	0.632	0.591	0.673	10.5 >	65%	60%	33%	85%	< 0.0005
ABONE1	0.618	0.576	0.659	1.5 >	66%	60%	48%	75%	< 0.0005
OST1	0.644	0.604	0.684	-2.9 >	80%	43%	30%	87%	< 0.0005
BW1	0.591	0.549	0.633	75.5 <	69%	41%	26%	81%	< 0.0005
OSIRIS1	0.641	0.601	0.681	0.5 <	63%	57%	31%	83%	< 0.0005
				1.5 <	76%	44%	30%	86%	< 0.0005

¹Osteoporosis status: T-score ≤ -2.5. SCORE: Simple calculated osteoporosis risk estimation; ORAI: Osteoporosis risk assessment instrument; ABONE: Age, body size, no estrogen; OST: Osteoporosis self-assessment tool; BW: Body weight; OSIRIS: Osteoporosis index of risk; PPV: Positive predictive value; NPV: Negative predictive value.