Variability of platelet aggregation in patients with clopidogrel treatment and hip fracture: A retrospective case-control study on 112 patients

Table 2 Bleeding, erythrocyte transfusions and adverse events up to 3 mo follow-up

Variable	Control (n = 84)	Responder (n = 20)	Non-responder (n = 8)	P-value
Peroperative bleedning (mean ± SD)	350 (0-1800)	300 (50-1500)	150 (50-550)	0.82
Any erythrocyte transfusion, n (%)	54 (64)	13 (65)	6 (75)
Number of transfusions, median (range)	2 (0-10)	1 (0-6)	2 (0-6)	1.02
Time to surgery (h), mean ± SD	21 (± 12)	45 (± 26)	28 (± 33)	0.0032
Adverse events
Any AE, n (%)	31 (37)	9 (45)	5 (62)	1.03
Type of AE, n1
Deceased, n	14	2	3
Hip related	6	2	0
Cardiovascular	8	1	3
Infection	14	9	4
Other	24	6	3

¹Several patients had more than 1 AE;

²ANOVA;

³χ² test. Bonferroni correction has been applied to all P-values.