Role of osteoclasts in regulating hematopoietic stem and progenitor cells

doi:10.5312/wjo.v4.i4.198

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Oct 18, 2013 (publication date) through Nov 22, 2024

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World Journal of Orthopedics

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2218-5836

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Orthop. Oct 18, 2013; 4(4): 198-206
Published online Oct 18, 2013. doi: 10.5312/wjo.v4.i4.198

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Figure 3 Increased bone mass is associated with an increased hematopoietic stem cell pool. Hematopoietic stem cells (HSC) are located in bone marrow cavities with surrounding niche cells. Increased bone mass due to either increased osteoblast activity or reduced osteoclast activity likely contributes to HSC expansion.

Citation: Miyamoto T. Role of osteoclasts in regulating hematopoietic stem and progenitor cells. World J Orthop 2013; 4(4): 198-206
URL: https://www.wjgnet.com/2218-5836/full/v4/i4/198.htm
DOI: https://dx.doi.org/10.5312/wjo.v4.i4.198